|
Criteria for diagnosis of ARVD [5] |
| I. Global and/or Regional Dysfunction and Structural Alterations* |
| • Major |
| Severe dilatation and reduction of right ventricular ejection fraction with no (or only mild) left ventricular impairment |
| Localized right ventricular aneurysms (akinetic or dyskinetic areas with diastolic bulging) |
| Severe segmental dilatation of the right ventricle |
| • Minor |
| Mild global right ventricular dilatation and/or ejection fraction reduction with normal left ventricle |
| Mild segmental dilatation of the right ventricle |
| Regional right ventricular hypokinesia |
|
|
| II. Tissue Characterization of Wall |
| • Major |
| Fibrofatty replacement of myocardium on endomyocardial biopsy |
|
|
| III. Repolarisation Abnormalities |
| • Minor |
| Inverted T waves in right precordial leads (V2 and V3) in people aged >12 years, in absence of right bundle branch block |
|
|
| IV. Depolarization/Conduction Abnormalities |
| • Major |
| Epsilon waves or localized prolongation (>110 ms) of the QRS complex in right precordial leads (V1 - V3) |
| • Minor |
| Late potentials (signal-averaged ECG) |
|
|
| V. Arrhythmias |
| • Minor |
| Left bundle branch block type ventricular tachycardia (sustained and non-sustained) by ECG, Holter or exercise testing |
| Frequent ventricular extra-systoles (>1000/24 hours) by Holter |
|
|
| VI. Family History |
| • Major |
| Familial disease confirmed at necropsy or surgery |
| • Minor |
| Family history of premature sudden death (<35 years) due to suspected right ventricular dysplasia |
| Familial history (clinical diagnosis based on present criteria) |
|
*Detected by echocardiography, angiography, magnetic resonance imaging, or radionuclide scintigraphy. The diagnosis of ARVD would be fulfilled by the presence of two major, or one major plus two minor criteria or four minor criteria from different groups. |
Jain et al. Journal of Cardiovascular Magnetic Resonance 2008 10:32 doi:10.1186/1532-429X-10-32 |